I'm an English professor who does various kinds of computational analysis on large text corpora (so things like string handling, XML, and regex are really important to me). I've been known to write programs that take three weeks to run in Java, so I'm always looking for ways to make my programs fast without resorting to C. Nothing against C. It's one of my favorite languages. It's just not a lot of fun for string processing.
Basically, I always want to go high and fast with my languages, and that's one of the reasons I like Lisp. It's a super high level language, but (in my usage patterns) it outperforms languages like Ruby (which I adore) and Java (which I find increasingly annoying).
Now, my particular usage is perhaps a bit obscure, but it may generalize to other areas. I can't believe I'm the only one doing lots of text processing who wants a fast, high level language. In the end "web application programming" is really just a special case of text processing, so it may align with PG's goals at some more fundamental level.